87 



solution,^) Weight of pancreas, 53.705 grams; estimated total number 

 of islands 737,4('»0; number of islands per milligram of fresh pancreas, 

 14.89. An attempt was made to determine the comparative distri- 

 bution of the islands in the 3 portions of the pancreas, the head, 

 body and tail. Eeduction in the head, however, proceeded even faster 

 tlian previous experience had led me to suppose, so that a smaller 

 <]uantity than was desirable was counted. From the splenic end 

 2114 islands were found in 180 milligrams of pancreas; from the 

 body 1835 islands were found in 121 ujilligrams of pancreas; from the 

 head 404 islands were found in l(i milligrams of pancreas. The relative 

 distribution of islands of Langerhans in the 3 parts of the pancreas 

 were in this subject 11.74, 16.16 and 25.25 per milligram of fresh 

 pancreas from the tail, body and head respectively. 



Subject No. 8, March 29, 1912, Fihpino subject, 29 years old, 

 of about 135 pounds weight; pancreas injected with 1 : 50,000 janus 

 green in Einger's solution from the coeliac axis. Weight of pancreas 

 61.511 grams; estimated total number of islets 662,166; number of 

 islands per milligram 10.76. 1330 islands of Langerhans were found 

 in 143 milligrams of the duodenal portion, 1307 in 122 milligrams 

 of the body, and 2218 in 186 milligrams of the splenic portion, giving 

 a total of 4855 in 451 milligrams of pancreas. Eeducing these figures 

 to number of islands per milligram of pancreas we have 9.3 islands 

 of Langerhans per milligram for the duodenal portion; 10.71 for the 

 body; 11.92 for the splenic portion. 



Subject No. 9, April 16, 1912, Filipino subject, 45 years old, 

 of about 150 pounds weight; pancreas injected from the coeliac artery 

 with 1 : 40,000 janus green in Einger's solution. Weight of pancreas 

 55.923 grams; estimated total number of islands 208,869: number of 

 islands per milligram 8.72. 962 islands of Langerhans were found 

 in 230 milligrams of the duodenal portion, 1557 in 577 milligrams of 

 the body, and 1628 in 306 milligrams of the splenic portion, giving 

 a total of 4147 in 1113 milligrams of pancreas. Eeducing these figures 

 to number of islands per milligram of pancreas, we have 4.18 islands 

 of Langerhans per milligram for the duodenal portion, 2.7 for the 

 body and 5.32 for the splenic portion.^) 



1) The Ringer's solution is that recommended by Locke for the Mam- 

 malian heart, minus the dextrose. It consists of NaCl-0,9%, CaClj- 0,024%, 

 KCl -0,042% and NaHCO3-0,02%. 



') After obtaining this data from the blotted and weighed portions, the 

 pancreas and the three portions in weighing tubes were placed in an oven at 



