88 



With the exception of number 2 this pancreas contains the small 

 est total number of islands and the smallest number of islands per 

 miUigram of pancreatic tissue found in this series. In table 1 and 

 table 2 is given a summary of the results of the enumeration of islands 

 of Langerhans in the pancreas of these 7 normal human individuals. 



Table I. 



Counts of Islands of Langkrhans in Normal Human Pancreas. 



Table II. 



Distribution of Islands of Langerhans in the Human Pancreas expressed as 



number of Islands per Milligram of Pancreas. 



Age 



Body \^j^' 

 weight 

 in lbs. P^^C'-eas 



No. of Islands per Milligram of Pancreas 



Splenic 

 portion 



Body 



Duodenal 

 portion 



Total 

 pancreas 



The relative distribution of islets in subjects 8 and 9 is, in general, 

 except for the much higher island content found, in accord with the 

 results obtained by Opie, Sauerbeck, Laguesse and Heiberg, all 



90 to 100* C. for 24 hours and dried to a constant weight. This was done 

 in order to test the accuracy of this method of estimating the number of 

 islands of Langerhans. The pancreas itself lost 79,3% of its blotted weight, 

 the duodenal portion 76,1%, the body 76,6%, and the splenic portion 74,6%. 

 It is thus seen that with a little practice one can extract practically the 

 same amount of water from the different portions and from the main mass 

 of the pancreas. As this pancreas stained well and a comparatively large 

 amount from the most varied portions was counted, the relative distribution 

 of the islets shown here probably represents the true one for this pancreas. 



