adthor's abstract of this paper issued 

 by the bibliographic service october 6. 



THE NORMAL SHAPE OF THE MAMMALIAN RED 

 BLOOD CORPUSCLE 



LESLIE B. AREY 



From the Anatomical Laboratory of the Northwestern University Medical School^ 



ONE FIGURE 



CONTENTS 



A. Introduction 439 



B. Historical 440 



1 . Results from drawn blood 440 



2. Results from circulating blood 447 



3. Results from fixed material 449 



C. Observations 451 



1. Experimentation with drawn blood 451 



2. Examination of circulating blood 460 



3. Action of fixatives 463 



D. Discussion 465 



E. Summary '. 470 



F. Bibliography 471 



A. INTRODUCTION 



It has been a classical teaching that the normal shape of the 

 mammahan red blood corpuscle is that of a biconcave disc. 

 Within the last decade and a half, however, a few workers have 

 vigorously assailed this view and have asserted that intravitally 

 the erythroplastid is concavo-convex, i.e., has the form of a cup 

 or bell, and that the biconcave disc first appears after blood is 

 drawn from the vessels. According to this latter view, the cup 

 is the normal form, the disc the derived one. 



That under certain conditions cup-shaped corpuscles can 

 actually be found in ordinary preparations of drawn blood, in 

 fixed tissues, and even in circulating blood no one will deny; 



1 Contribution No. 49; May 25, 1917. 



439 



