152 GANGLION-GLOBULES. 
Remak as existing upon these fibres. The similarity between 
the organic fibres and that which I have described as the 
earlier condition of the white nervous fibres, might be adduced 
as an objection to my description of the formation of nerves, 
and it might be said, that that form seemed to be the earlier 
form of the white nervous fibre, because the organic nerves 
were developed earlier than the white, and, therefore, organic 
fibres were the only ones present in the first instance. Ob- 
servation of the actual transition, as represented in pl. IV, 
fig. 8, ec d, would, however, refute this argument. Each pale, 
nucleated fibre becomes a white nervous fibre, as an immediate 
consequence of the formation of the white substance, which 
is probably a secondary deposit upon the internal surface 
of the hollow fibre. The formation of this white substance, 
which, according to analogy, must occur in every one of the 
minutest fibres, either does not take place at all im the organic 
fibres, or does so at a much later period, and their peculiarity 
therefore consists in their remaining stationary at an earlier 
stage of development, and either never attaining to the higher 
development of ordinary nerves, or only at a much later period, 
(a point which might be decided by comparing their numbers 
in old and young individuals.) One can conceive that the 
function of the organic nerves, whether it be actually a che- 
mico-vital one, or consist merely in the production of in- 
voluntary motion, requires less-developed nerves, in the same 
way that the involuntary muscles do not attain the same de- 
gree of development as the voluntary. 
2. Ganglion-globules. 
These occur in the gray substance of the brain and spinal 
cord and in the ganglia, having generally the appearance of 
comparatively large granulous globules, enclosing a round vesi- 
cle, placed eccentrically, and which again exhibits in its 
interior one or two small dark points. According to Remak, 
two of these vesicles sometimes occur in one globule. Valentin 
(Nov. act. Acad. Leopold. xviii, p. 196), calls attention to 
the similarity between their composition and that of the egg, 
he compares the vesicle of the ganglion-globules to the germi- 
nal vesicle, their parenchyma to the yelk-substance, and ascribes 
