44 HUBER. [Vol. XVI. 



glycerine, I was, however, able in a number of instances to 

 trace the straight process of a sympathetic cell for some dis- 

 tance from the cell body, and in one preparation of the pharyn- 

 geal mucous membrane and the oesophagus of a frog prepared 

 as above stated, a straight process coming from a sympathetic 

 cell, which divided into two branches, was clearly made out. 

 These branches could be traced toward a small gland situated 

 in the upper part of the oesophagus, where both underwent a 

 second division ; from here one of the resulting branches could 

 be traced on to one of the alveoli of the gland, where it was 

 lost to view. The appearance here presented seemed to indi- 

 cate that the straight process extended toward the periphery, 

 and in this case innervated the small gland above mentioned, 

 although the ultimate endings on the gland cells could not be 

 made out. In the few cases seen by me, where the straight 

 process branched, this did not simulate a "T"-shaped branching 

 as described by Smirnow; the branching was usually at an acute 

 angle. The arrangement seen by him I should regard as acci- 

 dental. The observations made by me led to the conclusion 

 that the straight process is the neuraxis of the unipolar sym- 

 pathetic cell of Amphibia, innervating gland and non-striped 

 muscle tissue, as my observations on the bladder of the frog 

 would show. This conclusion is, therefore, wholly in accord 

 with the following statement made by Kolliker (25): "Die 

 geraden Fasern sind nicht Dendriten oder Protoplasmafortsat- 

 zen zu vergleichen, sondern einfach Achsencylinderfortsatze der 

 betreffenden Zellen, die zu Muskelfasern treten und hierbei 

 Verastelungen zeigen." 



The statement has been made that the sympathetic neurons 

 of Amphibia were unipolar cells. As an exception to this, I 

 may say that the sympathetic cells found in the wall of the 

 intestinal canal (stomach, small and large intestine) of frogs are 

 distinctly multipolar, as the two cells reproduced in PI. Ill, 

 Fig. 1 1, may show. These cells were sketched from a prepara- 

 tion of the large intestine of a frog, stained, intra vitani, in 

 methylene blue, and fixed in ammonium picrate ; in the figure 

 the purplish color assumed by methylene blue stained tissue 

 when fixed in the picrate is not reproduced. The cell body of 



