68 HUBER. [Vol. XVI. 



in such sections the sympathetic cells are not so clearly shown, 

 by reason of the fact that many of the processes are cut from 

 the cells, yet the relation of the dendrites and pericellular 

 plexuses to the cell body and capsule of the sympathetic cells 

 of the ganglion is more clearly shown than in ganglia studied 

 as a whole. 



Sympathetic Neurons of Mammalia. 



All writers who have reported observations made with the 

 Golgi or methylene blue method are agreed that the great 

 majority of the sympathetic neurons are multipolar. Dogiel 

 (40) states that near the poles of the sympathetic ganglia bipolar 

 and unipolar cells are to be found. Their number is relatively 

 small. My own observations lead to the conclusion that such 

 cells are usually found between the afferent and efferent nerve 

 fibers of the ganglion. In the protoplasm of all these cells 

 chromophile granules are seen ; in this respect my observations 

 are in accord with those made by Dogiel (40). 



The nucleus is usually only imperfectly stained in methylene 

 blue, more often of a diffuse blue, which may be of a darker or 

 a lighter hue than the cell body. Nucleoli are only rarely seen 

 with this stain, although they are readily found in preparations 

 stained in alum carmine. 



In some Mammalia, namely, the rabbit, hare, and guinea pig, 

 sympathetic cells with two or even three nuclei are found, as 

 has been shown by Remak (44), Guye (42), Schwalbe (15), and 

 more recently Apolant (43). Schwalbe and Apolant explain this 

 curious phenomenon by stating that it is the result of an incom- 

 plete cell division, the nucleus dividing but not the protoplasm, 

 and the latter has shown that the multiplication of the nuclei 

 takes place by an amitotic cell division, which may be recog- 

 nized in embryo rabbits as early as the third week. Apolant 

 reaches the following conclusions concerning this point: " Ich 

 glaube daher, dass die Bildung der beiden Kerne in einem 

 innigen Zusammenhange mit den Wachsthumsverhaltnissen der 

 Zelle steht, der Art, dass die anfangliche, iiberwiegende Aus- 

 bildung des Kernes zu einer Theilung desselben fuhrt, welche 



