we) 
bo 
E. V. COWDRY 
SUMMARY 
In the thyroid glands of normal guinea-pigs the reticular 
material is not invariably found between the nuclei and the 
follicular lumen, as is generally supposed, but in some cases under- 
goes an active migration to the opposite pole of the cell, which, 
together with other evidence at hand, indicates the existence of 
a reversal in physiologic polarity whereby the secretion is dis- 
charged directly into the circulation, instead of being first stored 
within the follicles. 
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