No. 3.] PERIPHERAL NERVES. 683 



shown in Fig. i. The connective tissue was then united over the bone 

 tube by means of four to six buried chromatized catgut sutures, and the 

 edges of the epidermis brought together by silk sutures. By closing the 

 wound in this way it was found that, while the silk sutures might break 

 through, the deep sutures would aid the connective tissue in uniting over 

 the bone tube and keeping it in place. 



Experiment 2y. — May 30, 1894. 



Young mongrel. | grni. morph. sulph. injected. 



Operation. — The ulnar of the left side was exposed for a distance of 

 8 ctm., and resected to the extent of 7 ctm. The ends of the resected nerve 

 were inserted into the ends of a bone tube about 8 ctm. long, and held in 

 place by a catgut suture passed through the nerve and bone tube, and the 

 wound closed. 

 Exainination. — June 4, 1894 (five days after operation). 



Epidermal wound open, connective tissue healed over bone tube, and 

 covered with healthy granulations. On removing the granulation tissue a 

 transparent flat band attached above and below to the resected ulnar could 

 be recognized, presumably the implanted bone tube. Electrical stimulation 

 of peripheral ulnar stump showed it to be degenerated. 



The nerve was hardened in Flemming's solution, and stained in safranin 

 and licht griin. 



Experiment 28. — May 30, 1894. 



Full-grown shepherd dog. Hypodermic injection of | grm. morph. 

 sulph. 



Operation. — The left ulnar was resected 6 ctm., and the resected ends 

 inserted into a bone tube, and retained in place by catgut sutures. Wound 

 closed. 

 Exatnination. — June 9, 1894 (ten days after operation). 



The greater portion of the wound healed by first intention. On exposing 

 the ulnar the implanted bone tube was not recognized. The end of the 

 central stump was slightly enlarged. The peripheral ulnar was degenerated, 

 as shown by electrical and mechanical stimulation. 



The nerve was hardened in Flemming's solution, and stained in safranin 

 and licht griin. 



The same physiological result was obtained in experiment 29. The 

 nerve was removed, hardened in Miiller's fluid, and stained in anilin blue 

 and safranin. 



Experiment 30. — Dec. 15, 1893. 



White and brown mongrel. | grm. morph. sulph. injected, followed by 

 ether. 



Operation. — The left sciatic was exposed, and resected to the extent of 

 3 ctm. The central and peripheral ends of the nerve were drawn into the 

 ends of the bone tube, and sutured in this position. Wound closed. 



