698 HUBER. [Vol. XI. 



tissue bundles of the epineurium, also between the junction of 

 the central ulnar stump and the central end of the implanted 

 segment, and between the peripheral ulnar and the peripheral 

 end of the implanted nerve. From the central and peripheral 

 wound they may be traced for a short distance between the 

 nerve fibres of the implanted segment, in less number between 

 the nerve fibres of the peripheral and central ulnar in the 

 neighborhood of the wounds. I was not able to find any poly- 

 nuclear leucocytes within the sheath of Schwann of the nerve 

 fibres in the transplanted segment, nor within the ends of the 

 nerve fibres of the central and peripheral stump of the ulnar. 

 The nerve fibres of the peripheral and central portion of the 

 ulnar are apparently of normal structure, the axis cylinder is 

 not interrupted, and the myelin presents a normal appearance. 

 That the fibres of the peripheral end possessed conductivity is 

 shown by the fact that the muscles supplied by the ulnar con- 

 tracted when the nerve was cut about 3 ctm. below the periph- 

 eral wound. The "traumatic degeneration," as described by 

 Biinger, Stroebe, and others, extends only a short distance 

 along the fibres of the central and peripheral ulnar, and is a 

 process differing essentially from the " secondary degeneration," 

 which involves the entire peripheral portion of the severed 

 nerve. In the immediate neighborhood of the trauma the 

 myelin is broken up into fragments, and in some of the fibres 

 the sheath of Schwann is filled with a granular debris, staining 

 a gray-black in osmic acid. The axis cylinder is, as a rule, 

 unbroken, and can be seen imbedded in the myelin. 



During the third day segmentation of the myelin in the 

 implanted fibres continues, and the fibres begin to show a very 

 irregular shape, many of them showing nodular enlargements, 

 in which are found one or several large fragments of myelin ; 

 these alternate with segments of the nerve of much smaller 

 diameter, composed largely of proliferated protoplasm in which 

 may be imbedded smaller drops or granules of myelin. A 

 chemical change has taken place in many of the fragments of 

 myelin, evinced by the way in which they stain with osmic 

 acid and safranin. In a normal nerve, hardened in osmic acid 

 (Flemming's solution) and stained with safranin, the myelin 



