284 GEO. S. HUNTINGTON 



'heart' unite secondarily with the luniina of the extracardiac 

 strands first developed. Federowicz states that the Ijrmphatic 

 vessels in the inmiediate neighborhood of the hearts cannot be 

 demonstrated by injection prior to the establishment of the 

 above outlined connections. Federowicz's preliminary account 

 is very brief and not completely clear on some points. Part 

 of the difficulty of his presentation seems to lie in his recognition 

 of the fact that his results do not agree with those of previous 

 observers, among whom he quotes Kollicker, Golubew, Rouget 

 and Clark. His evident disinclination to disagree with these 

 investigators, in spite of his divergent results, leads him, how- 

 ever, to make some curious and contradictory statements. He 

 thus attempts to argue from his findings for a centrifugal exten- 

 sion of his early independent extracardial lymphatic anlages. 

 The parental wish seems to influence this thought to a degree 

 which seriously detracts from its scientific value. He states 

 on page 296 of his preliminary communication, above quoted, 

 as follows: 



Vergleicht man nun den oben geschilderten Prozess der Zellstrang- 

 bildung aus der Wand des von der Venenwand entstandenen Lymph- 

 herzens, die Ausbreitung der Strange in der Umgebung der Herzen, 

 das Entstehen der Lichtung in denselben, die Klappenbildung und die 

 Vereinigung der Lichtung der Strange mit der des Lymphherzens, mit 

 dem spater an derselben Stelle ausgebreiteten Lymphgefassnetz, so 

 kann man nur den Schluss ziehen, dass dasselbe aus jenen Zellstrangen 

 hervorgegangen ist. 



So far Fedorowicz describes his own observations in the devel- 

 opment of cellular mesenchymal strands, the interQellular for- 

 mation of spaces within these strands, their union to form lym- 

 phatic vessels of longer extent, lined by a lymphatic endothelium 

 developed in situ, and the establishment of secondary connec- 

 tions in a centripetal direction of these extracardial early lym- 

 phatic spaces with the intracardial spaces of the lymphhearts. 

 This primary union of the independent lymphatic anlages takes 

 place from the pericardial periphery toward the interior of the 

 heart. If a centrifugal process were involved it would seem that 

 this is the crucial point for its manifestation and that the early 

 lymphogenesis would proceed from the lymphheart toward the 



