No. 3-] STUDY OF THE NERVE CELL. 457 
presence of nutriment carry on the processes of anabolism and 
katabolism at the same time. Under the conditions of our 
present experiments, anabolism is impossible, while katabolism 
is possibly unimpeded or accelerated. Note the slight shrink- 
age which occurs +n a few of the control ganglia. 
Shrinkage in nuclei of control cells probably occurred to a 
slight degree in all experiments where simple sodium chloride 
solution was used. It never reached the point at which the 
nucleus began to show indentations. In Ringer's solution, or 
sn salt solution saturated with calcium phosphate, no change 
in this respect could be detected, even for long periods. This 
agrees in the main with recent work by Locke! upon the 
‘nfluence of so-called “normal > solutions on the form of curve 
of muscle contraction, salt solution making the curve higher 
than normal. A slight effect tending toward that produced by 
stimulation is no more than we should expect in transferring 
ganglion cells from blood to any normal solution. In experi- 
ment g the control nucleus takes a peculiar course. It is seen 
to swell slightly for the first two hours, it then comes back to 
normal and continues to shrink, until in seven hours it has lost 
19 % of its original bulk. I have, as yet, no adequate explana- 
tion for this case. It stands alone so far as my observations 
go. Upon diluting a normal solution with distilled water, I 
have observed similar swelling of nuclei. This fact, however, 
throws little light on the present instance. 
Experiments 1 to 23 were all made with the single purpose 
of observing changes which might occur in ganglion cells dur- 
ing stimulation. But few in this group require fuller state- 
ment than is already given in the table. 
In experiment 3 the cells were kept under observation at 
intervals, for six days. Camera drawings were made, at least 
one a day, during the whole time. Measurements were taken 
to begin with, and at the end of three hours. As the mirror of 
camera was moved, it is not possible to compute volumes accu- 
rately beyond this time. Measurements were omitted under 
the impression that camera drawings would serve instead. 
1 Locke, Die Wirkung der physiologischen Kochsalzlisung auf quergestreifte 
Muskein. Pfliiger’s Archiv, Bd. 54, S- 501-524- Bonn, 1893. 
