Irving Hardesty 93 
As before noted, cells of this type are less frequent in my prepara- 
tions and such have been very infrequently noted in the literature. 
Brodmann ™ noted what were evidently cells of this type in a glioma of 
the thalamus opticus stained by Weigert’s neuroglia method. He de- 
scribes such cells as especially abundant in the zone of growth of the 
tumor and refers to them as “ Bindungszellen der Gliafasern.” Reinke 
(loc. cit.) in one of his illustrations shows two of the larger cells with 
joining processes. His stain, however, does not show the abundance and 
nature of the cytoplasm marking the type as is shown by the Benda 
method. 
2. The second type of cell to which I wish to call attention (b, Figs. 
2 and 3) is apparently a transition form of the first. It possesses the 
large vesicular nucleus as in the first type, but its cytoplasm is modified. 
About the nucleus the cytoplasm is as compact as in the first type but 
in the outer zone of the cell it grades into loose scattered granules 
which may be quite absent from the processes. Thus the cell is par- 
tially a phantom of the first type, having for its outline the boundaries 
of the inter-axone space it occupies. Neurogha fibers are easily dis- 
tinguished passing through the cell. They may be followed into it by 
way of one process, then usually along one side in the less obstructed 
outer zone, and out by way of another process. Or, in passing through 
the cell, a fiber may involve a portion of the more dense cytoplasm about 
the nucleus. It cannot be said with confidence that fibers are inter- 
rupted in passing through the cytoplasm. Fibers often appear as if 
having been spun out of the cytoplasm and often appear to terminate 
in it, but such appearances must more generally be considered as being 
due to the knife. No fibers have been observed terminating in the 
cytoplasm in a cone-like end as noted by Yamagiwa “ in his preparations, 
which cone was described by him as a part of the cell cytoplasm and 
as an evidence that the fibers are processes of the cell. The cytoplasm 
about the nucleus possesses short branches. These always point toward, 
and sometimes into, the spaces between the neighboring nerve fibers 
and thus represent portions of the original processes of the cell. 
3. More often a much smaller amount of cytoplasm is present (stains) 
and this is always in the immediate vicinity of the nucleus forming an 
irregularly-shaped, granular zone about it. Such cells never fill the 
inter-axone space. Usually short projections are maintained and these, 
Brodmann. Ueber den Nachweis von Astrocyten mittelst der Weigertschen Glia- 
farbung. Vortrag in der Naturwissenschaftlichen Gesellschaft zu Jena. Jan., 1899. 
2 Yamagiwa. Eine neue Firbung der Neuroglia zugleich ein Kleiner Beitrag zur 
Kenntniss der natur von den Glia-fasen. Virchow’s Archiv, Bd. 160, 1900. 
