114 The Cardiae Glands of Mammals 
but as the membrane becomes thinner they become first restricted to 
the deeper portion of the mucosa and finally break through the museu- 
laris mucosa to extend into the submucosa. In the latter case the 
muscularis mucose is interrupted opposite the follicle, the superficial 
tissues of which are continuous through the gap with the diffuse adenoid 
or Xe 
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Fria. 2. Two foveolx gastrice from the cardiac region of man. 
< 280. The mucous theca becomes reduced, in the lower half of 
the foveola, to a very narrow margin along the lumen. The cells 
in this position are shorter and a number of deeply staining 
mitotic figures are seen. A few polymorphonuclear leucocytes 
and lymphocytes are to be seen in the epithelium. The cells of 
the interstitial tissue are largely Unna’s plasma cells with a few 
polymorphonuclears and eosinophiles. 
‘ 
fe) 
and stomach-pit, commonly employed. 
tissue of the mu- 
cosa (Fig. 1). 
There are rea- 
sons, which will be 
discussed later, for 
regarding the car- 
diac glands as de- 
cadent structures. 
On this account it 
is desirable to se- 
lect for prelimi- 
nary description 
those glands in 
which this feature 
is least apparent. 
Such are the 
glands of the thin- 
ner distal portion 
of the mucous 
membrane of the 
cardiac zone. To 
avoid confusion, I 
shall call the fun- 
nel-shaped depres- 
sions of the sur- 
face into which the 
glands open, foveo- 
le, as being a pre- 
ferable term to the 
compound expres- 
sions  gland-duct 
The epithelium of the free surface was lost in most of the material at 
my disposal, but where it was retained resembled in all essential points 
that of other stomachs. The epithelium of the upper portion of the 
foveola is represented in Fig. 2 and is very similar to the epithelium of 
