BK. Re Bensley 117 
mains of it may usually be recognized in the interior of the cell. In 
some cases the proximal mass of secretion only is present so that the cell 
has a protoplasmic distal border along the lumen, and reminds one 
strongly of Krause’s figures of the mucin-forming cell of the retro- 
lingual gland of Erinaceus at an early stage of mucin formation. 
The mitoses seem to be entirely confined to the cells of the bottom of 
the foveole and adjacent portions of the gland. I have not observed 
a single instance of cell division in the surface epithelium nor in the 
cells at the bottom of the gland, although cells near the foveole may 
divide even when they contain a good deal of secretion. The great 
mitotic activity at the junction of gland and foveola, as well as the 
eradual transition from this point in both directions leads me to believe 
that this is the site of the reproduction of both the surface epithelium 
and the glandular epithelium, both of which are probably replaced 
when lost by a gradual migration of cells from the point at which they 
are reproduced. 
Passing on, now, to the complex glands of the beginning of the area 
this simple relation of the cellular elements to one another is found to 
be by no means the rule. Many anomalies are seen. The cells of the 
lower ends of the foveole while similar in the majority of cases to those 
already described may lose their mucigenous border altogether and 
appear protoplasmic throughout. Again the transition into the gland 
may not occur at all or be little marked, the secretion filling only a 
small portion of the free border of the cell even in tubules remote from 
the main duct. Thus, one may see side by side in the same gland, cells 
or tubules equally remote from the duct which exhibit the two extremes 
of secretion, some filled with stored-up product, others containing but 
little. These are, obviously, differences of physiological equilibrium 
and do not introduce any new difficulties in the way of interpreting the 
glands. In this region the mitoses, as in the case of the more typical 
glands, are practically confined to the upper portions of the ducts and 
the adjacent portions of the gastric foveole. There is also in the com- 
plex glands near the cesophageal epithelium a great variability in the 
size of the terminal branches of the tubules which compose the gland, 
some being many times as large as others. 
The important question now arises, what is the nature of the stored- 
up secretion in these cells? The transition to the surface epithelium 
and the probable mode of reproduction of the glandular elements as 
indicated by the mitoses, both suggest that the secretion may be chemic- 
ally, as the cell is genetically, related to that of the surface epithelium, 
that is to say, may consist largely of mucus. On the contrary Schaffer, 
