R. R. Bensley 12: 
Ot 
The character of the cells lining the deep ends of the foveole and 
the glands differs according to whether the animal is mature or other- 
wise. Fig. % represents the upper end of a cardiac gland and the 
adjacent portion of its infundibulum from an animal about six weeks 
old. The preparation was stained with 
Mayer’s muchematein followed by acid 
rubin. The upper cells present two dis- € 
tinct zones; a larger distal zone filled or 
with closely-packed granules of mucigen, =: 
black in the figure, which were stained 
blue by the muchematein, and a proxi- 
mal protoplasmic zone containing the 
shghtly flattened nucleus. Proceeding 
down the gland it is presently observed 
that the mass of mucigen exhibits an 
hour-glass constriction in the center, ow- 
ing to a concentration of the protoplasm 
of the cell at that point, and still further 
down, is completely divided into two mass- 
es, one of larger size near the nucleus, and 
a smaller band along the free border. 
On close inspection, the bridge of pro- 
toplasm separating these two masses is 
found, in sublimate preparations to be 
studded with minute granules which stain 
intensely in eosin or rubin 8. At the 
lower ends of the foveole the proximal 
or internal mass of mucigen disappears 
altogether and in the whole of the 
gland proper only a slightly blue stained 
band is discernible along the free borders 
of the cells. As the internal mass of tee andwacaoone porHonton mate 
mucigen diminishes in size there is, how-_ toils oeeuatatonetainen in ane 
ever, a -corresponding increase in the cea SER aiacee 
number of rubinophilous granules which '{'#%e¢ Pick ip Beure. 
occupy, in the upper portions of the glands one-third or more of the 
cell near the lumen. 
These granules are not zymogen granules, because they are not vis- 
ible in the fresh cell and because Greenwood, —, has shown that the 
cardiac mucous membrane of the pig yields, when tested by Griitzner’s 
method only one-eightieth as much pepsin as the fundus region. ‘The 
