130 The Cardiac Glands of Mammals 
obvious constriction. In connection with the formation of this left 
non-glandular region there is an enlargement of the ccecal left ex- 
tremity of the stomach, in some cases to such an extent that it exceeds 
in size all the rest of the stomach. 
In Mus musculus, both the “ Grenzfalte” and the external constric- 
tion are little marked and the stomach of this form, therefore, repre- 
sents, with the exception already noted, the simplest type known in the 
Myomorpha. 
The extensive cardiac gland zone described by Toepfer, 91, adjoining 
the opening of the cesophagus on the lesser curvature of the mouse’s 
stomach, did not occur in any of the numerous specimens examined by 
me. The glands of this region are relatively short, it is true, but they 
contain all the characteristic elements 
of the fundus glands. There are, 
nevertheless, cardiac glands in a dif- 
ferent situation. In a section across 
the line of junction of the two main 
divisions of the stomach it is seen 
pa ew Wc that there are 
Chentsllgpes=o 2s gf Bee oe yy Sas along the 
eons FS __. stattiedetheliom “ Grenzfalte ” 
y= oF Grenzmembran two or three 
rows of glands 
which may, I 
think, on ac- 
count of their 
structure, be properly designated cardiac glands. The epithelial and 
glandular portions of such a section are represented in Fig. 9. The 
gland nearest the “ Grenzfalte” is usually a simple crypt lined by cells 
like those of the surface epithelium, but not infrequently there are two 
or three glandular cells at the lower end of the tubule. These cells 
exhibit the usual structure of mucous cardiac gland cells and their con- 
tents stain readily in mucicarmine and muchematein. The simple 
crypt above described does not occur with the same frequency along the 
“ Grenzfalte” as the other glands, and if serial sections are not exam- 
ined may be readily overlooked. 
The transition between these cells, when present, and the surface 
epithelium is usually abrupt, but this probably is due to the shortness 
of the glands. The parietal and ferment-forming chief cells make their 
appearance in the third or*fourth tubule, the former being usually the 
first to appear. 
Cardiac Glands 
Fra. 9. Section across the junction of the right and left divisions of 
the stomach of Mus musculus. 500. Iron haematoxylin. 
