358 The Histogenesis of the Adrenal in the Pig 
In pigs of from 30 to 35 mm. a new element is added to the anlage. 
Immediately beneath the capsule there are seen collections of small cells, 
the nuclei of which stain deeply and are surrounded by very scanty 
cytoplasm. In thick sections (Fig. 5) these are seen to be arranged 
around the cortical portion in a mantle-like layer, from which offshoots 
are proceeding inward between the rows of cortical cells. ‘Towards the 
lateral aspect of the adrenal this mantle becomes very thin, or is even 
entirely lacking; but along its dorso-medial surface it is thick, and its 
Fie. 5. Pig 35 mm. Leitz obj. 3, oc. 4. 8. g., anlages of sympathetic ganglia; 
Man., mantle layer of cells; X., columns of cells connecting sympathetic anlages 
with mantle; Cor., cortical portion of adrenal; C., isolated portion of cortex; Cap., 
capsule of adrenal. Section 25 mm. mikrons thick. 
prolongations into the cortex are numerous and extensive. In this lat- 
ter region the capsule of the adrenal adjacent to the ganglia is much 
broken up, or even wanting over considerable areas; so that in these 
situations there is nothing between the ganglia and the cortical portion 
of the adrenal except the mantle of cells previously mentioned. Through 
the gaps in the capsule cellular strands, often of considerable size, con- 
nect the mantle on the inside with the ganglia on the outside. The con- 
nection is sometimes so intimate that what is seen in one section as a 
