STUDIES ON THE PANCREAS OF THE GUINEA PIG 



339 



In this connection it should be mentioned that animals kept with- 

 out food will eat their own faeces or anything else which may be 

 present in their cages. Accordingly all animals intended for this 

 experiment were kept in special cages over a wire grating which 

 permitted all refuse to drop through. 



In table 6 each number represents the average number of islets 

 per milligram in a series of sections 2 mm. thick taken at regular 

 intervals in the corresponding portions of the pancreas. The 

 splenic division includes the whole of the swollen extremity of 

 the omental division of the pancreas, the body the narrow portion 

 between the preceding division and the pylorus, the duodenal 

 division all the pancreas included in the mesoduodenum. 



TABLE 6 



Showing numher of islets of Langerhans in the pancreas of dogs after inanition, in 

 terms of number of islets per milligram of pancreas 



Series 1 . Inanition dogs 



INITIAL WEIGHT 

 OF DOG 



grams 



12,150 

 10,170 



SPLENIC DIVISION 



8.08 

 10.12 



6.2 



5.82 



DUODENAL 

 DIVISION 



5.9 

 4.58 



DURATION OF 

 INANITION 



days 



10 

 10 



Control {twenty-four hours fast) 



5,300 



16.8 



32.87 



15.8 



*In this series the two inanition dogs were members of the same litter, the two 

 controls were members of another litter. All were reared in the laboratory and 

 were approximately six months old. 



