SECRETORY FUNCTIONS IN HUMAN PLACENTA 523 



* Primargranula ' — which are seen microscopically to gradually 

 bring about the growth of definite secretory granules. Thus 

 it seems he denies the histogenetical correlation between plasto- 

 somes and secretory granules. His theory, though most dex- 

 terously proposed on the most profound proofs, is after all a 

 mere hypothesis. Besides, in consideration of the following 

 quotation, it will be quite clear how he holds the views that his 

 so-called ' Primargranula ' have a close relation with the genuine 

 cytomicrosomes in their formation, and that the latter do 

 correspond to a section of his ' Basalfilamente, ' and, further, that 

 the filaments are identical with Flemming's Mitom: 



Ich bin daher mit Solger der Meinung, dass auch in den serosen 

 Driisenzellen die Basalfilamente Teil eines Fadensystems si'nd, welches 

 nach der Bezeichnungsweise Flemming's dem sogennanten Cytomitom 



zugehoren wiirde Nichtganzausschliessendarf man jedoch 



zur Zeit die Moglichkeit, dass die Driisengranula eventuell von den 

 genuinen Plasmamikrosomen sich ableiten, welche nach unseren allge- 

 meinsten Erfahrungen immer innerhalb der Protoplasmafilamente liegen, 



also verdichtete Telle feiner Fadchen sind Da nun die 



Korperchen beiderlei Art (Primargranulis und genuine Mikrosomen) 

 morphologisch schwierig unterscheidbar sind, so kann eine verwand- 

 schaftliche Beziehung zwischen beiden zur Zeit wenigstens nicht abge- 

 lehnt werden, besonders da wir iiber die positive Bedeutung der genuinen 

 Plasmamikrosomen noch sehr im Unklaren sind (p. 390). 



And since it has already been clearly proved by the researches 

 of Meves ('07) that Flemming's Cytomitom agrees with our 

 plastosomes, it would appear that M. Heidenhain does not only 

 maintain the view that his 'Basalfilamente' exists as a water- 

 secreting apparatus as mentioned above, but at the same time 

 also supports, instead of disproving, the argument which re- 

 gards basal filaments as being the matrix for the formation of 

 secretory granules, as Altmann and others do. As regards 

 Mislawsky's view, it will be noted that he, in line with Levi, 

 takes the ground that as between plastosomes and secretory 

 granules there were no conspicuous conditions to be detected in 

 support of the existence of a formative relation between the two. 

 However, anent Mislawsky, it will be noted that the invalid- 

 ity of such a view has been exhaustively pointed out by a Belgian 

 cytologist, Duesberg, in comments noted for their profundity 



