528 GENCHO FUJIMURA 



Entering into details, Mulon stated that in the rabbit the 

 plastosomes, granular in form at first, change into minute 

 siderophil granules, and then diffuse siderophil substance, and 

 the lipoids will be formed from the latter. Athias ('12), who 

 examined a newborn bat, also seconded the argument of Mulon 

 for the most part, and argued that plastosomes produce the 

 lipoid first at their center and accumulate it there, and in sup- 

 port of his argument he stated that occasionally the cortex, 

 which has the same staining properties as plastosomes, could be 

 detected around the lipoid granules. Tsukaguchi certified to 

 an intermediate type of granules between the plastosomes and 

 the lipoid in the young interstitial cells, thus arguing that the 

 granular plastosomes develop and grow in size directly into the 

 lipoid granules, as are seen in the case of the luteal cells. In 

 short, the various investigators have not as yet come to an 

 agreement in their views as to the correlations between the 

 two, and yet it has been universally acknowledged by them 

 that as the cells grow and increase and the lipoids or vacuoles 

 appear plentifully, the plastosomes decrease in quantity in 

 inverse ratio. 



With regard to the organs other than the ovary, Mulon ('10 

 a, b) closely examined the suprarenal capsules of a guinea-pig 

 and rabbit, and stated that by the conglutination of the gran- 

 ular plastosomes was produced directly a substance (possibly 

 our lipoids) which has affinity for osmic acid (osmophil) or iron- 

 alum-haematoxylin (siderophil), and is introductory to the 

 formation of a vacuolar secreting matter to follow. Celestino da 

 Costa ('07), Champy ('09), and Colson ('10), also having experi- 

 mented on the cortical cells of the suprarenal of a cat, guinea- 

 pig, toad (Bombinator) and bat, have proved the same fact as 

 above. Bobeau ('11) also argued that when the parathyreoid 

 glandular cells of a horse form a certain effective product the 

 plastosomes should play an important part. And, besides, Engel 

 ('09), Mawas ('11), and Schultze ('11), each demonstrated the 

 plastosomes in the thyreoid and parathyreoid glands of a man, a 

 rabbit, and a frog, and, according to Duesberg, it was stated 

 that the plastosomes could be detected in the Langhans' cells 



