384, MINOT. (Vou. II. 
them, forming main cell bodies. I notice, also, a few cells which 
I suppose to be leucocytes, but see no other structures. By the 
end of the third month the cells have assumed nearly their defi- 
nite form; the protoplasm has increased in amount, and forms a 
large cell body around each nucleus, Cut 6. The network has 
become simpler and coarser, the meshes bigger, and the fila- 
ments fewer and thicker; in the matrix are numerous connec- 
tive tissue fibrils, not yet disposed in bundles, except here and 
there ; as they curl in all directions many of them are cut trans- 
versely, and therefore appear as dots. In older cords there is an 
obvious increase in the number of fibrils, and they form many 
bundles. In the cord at term the matrix contains mucin, and 
may be stained by alum hamatoxylin; at what period this re- 
Cut 7.— Section of the allantois from the umbilical cord of an embryo of three 
months; e¢, entoderm; es, mesoderm. X 340 diams. 
action is first developed I have not ascertained. I have ob- 
served nothing to indicate the presence of special lymph chan- 
nels in the cord at any period, but I have not investigated the 
point. Tait’s lymph channels are merely the intercellular spaces. 
The tube of allantoic entoderm increases very little in diame- 
ter after the second month; compare A and B, Cut 4. It is 
very persistent, appearing usually even in the cord at full term, 
at least in the proximal end, according to Kdlliker (Extwick- 
lungsges. 2te Aufl, p. 34). After the second month it is a small 
group of epithelioid cells, with distinct walls, irregularly granu- 
lar contents, and round nuclei; around the cells, ez¢, which may 
or may not show a remnant of the central cavity, there is a 
