65 



cell layers as they approach the lumen of the acinus undergo a 

 marked change. The cell outlines become indistinct, and finally, the 

 cell bodies disappear and the nuclei are set free. 



The nuclei become somewhat smaller and more rounded, and their 

 affinity for nuclear stains is proportionately increased. Eventually, 

 they assume, in all characteristics, the appearance of the bodies which 

 are found in such large numbers in the secretion of this type of acinus 

 as well as of the simple acinus previously described. 







••'•*.'■ /I '^^^ ■ ^-^ 



L^-:. %s .^ V"^ ' 1 ^^^'.„H' ; 



c. 



Fig. 2. A section from another part of the same gland as Fig. 1. Higher 

 magnification. d union between the two types of acinus, e the encircling band of 

 unstriped muscle. The other lettering as in Fig. 1. 



It seems more probable, then, that these circular bodies are the 

 extruded nuclei of the functional cells, and that the secretion of the 

 gland is produced at the expense of the cells. On the other hand, 

 the presence of the bodies is equally, or nearly equally, as constant, 

 and the bodies almost as numerous in the acinus of type V; yet, in 

 the latter there is only a single row of cells, with the exception of the 

 pearshaped intercalated cells, which are not numerous. Further — and 

 this is probably of more importance — no cells have been found in 

 the process of disintegration in the single-layered type of acinus. 



Neither have nuclei been observed in a state of transition — from 



Anat. Anz. XXXI. Aufsätze. 5 



