140 



the mucous layer where certain of the gastric glands open into the 

 lumen of the organ. These microphotographs which are taken at the 

 same magnification indicate a very considerable decrease in the dia- 

 meter and length of the epithelium cells in the more starved animal. 

 The cells of the gastric crypts in the less starved specimen show an 

 exceedingly vacuolated condition of the cytoplasm at the distal ends, 

 while deeper down and well surrounding the nucleus the cytoplasm is 

 denser and apparently more normal. These same cells in the case of 



Fig. 6. 



Fig. 7. 



Fig. 6. Photograph of stomach epithelium at region of one of the gastric crypts 

 of the animal starved for 4 months. Note the large nuclei and general large size of 

 the epithelial cells. 



Fig. 7. Photograph at same magnification as Fig. 6, of stomach epithelium of 

 animal starved for 16 months. Note the very considerable shrinkage of all tissue 

 elements. 



the more starved animal are more homogenous throughout, very little 

 of stainable substance is to be seen in the cytoplasm, in fact staining 

 with haematoxylin was much more difficult than in the preceding case. 

 The nuclei of these cells have in general shrunken about one-fourth of 

 the volume shown in the case of the less starved animal. 



As we pass down along the gastric glands evidences of greater 

 change are seen. Photograph 8 represents a cross section of several 

 of these glands cut so as to show the chief cells and in one gland 

 mucous cells. It will be noted that in this specimen (less starved) 

 the cells are fairly normal in appearance, the nuclei are prominent 



