142 



ment, closely packed together. The nuclei are large, and prominent. 

 The cytoplasm of the outer end of the cell is finely granular sometimes 

 showing small vacuoles, a condition which is maintained up to the 

 nucleus. From the inner end of the nucleus to the basement mem- 

 brane the cytoplasm is filled with minute, transparent vacuoles. This 

 fact would seem to indicate that degenerative processes in these cells 

 are progressive in their character and take place from the basement 

 membrane toward the distal ends of the cells. This condition is even 



Fig. 10. Fig. 11. 



Fig. 10 and Fig. 11. Photographs at same magnification of sections of the walls 

 of the small intestine of the animals starved for 4 and for 16 months respectively. 

 Note the great shrinkage of all the tissue elements in the specimen starved for the 

 longer period. 



more pronounced in the 16 months starved animal. Here we find the 

 inner ends of the cells completely filled with transparent vacuoles. 

 The outer ends are not so strongly vacuolated but show a much more 

 advanced stage of degeneration than is present in the less starved 

 animal. 



We have more Necturus under observation this year, some of 

 which are being fed on definite diets. A study of these together with 

 the material that we have on hand will furnish the bases for a more 

 extended report in which special attention will be paid to the cyto- 

 logical efi"ects of starvation. 



March 1, 1911. (Eingegangen am 25. März.) 



J 



