128 



HODGE. 



[Vol. VII. 



2 S 



O m 



TABLE VIII. 



Stronger Stimulation and Shorter Rest Interval. 



Time. 

 Cat No. 9 (45 seconds' rest 



to 15 seconds' work) .... 2 hrs. 



Cat No. 10 (intervals 15 

 seconds' rest to 15 sec- 

 onds' work) 2 " 



Two facts are apparent. First, with stronger stimulation, 

 naturally enough, the effect may be produced in two hours that, 

 with slight stimuli, it required ten hours to obtain. Second, the 

 length of rest intervals is of great importance. Although 

 No. 10 received exactly twice as much stimulation in the two 

 hours, the cells show considerably less change than those of 

 No. 9. 



Stimulation has brought out a functional differentiation of 

 some sort between the large and small cells of the spinal 

 ganglia. The large cells show the effects of work ; the small 

 cells very little, or not at all. The fact is too well marked to 

 pass by unnoticed. 



Considering all cells large which have one diameter 50 yu., or 

 over, and those small which have not, a count gives the follow- 

 ing result : — 



Cat No. ii. — First Thoracic Ganglia. 



In 100 large cells nuclei. 

 Shrunken. Not shrunken. 



Resting 5 95 



Stimulated 94 6 



In 100 small cells nuclei. 



Shrunken. Not shrunken. 



O ICO 



8 92 



A few fibres going to a ganglion, the vertebral branch, etc., 

 escape stimulation by our method. This accounts for the few 

 large cells which do not appear worked in the stimulated 

 ganglion. It cannot account for the multitude of small cells, 

 comprising numerically more than half the cells of the ganglion, 

 which do not show the effects of stimulation. After some 

 searching, a field was found (PI. VII, Fig. 2) in which every 

 nucleus was shrunken ; but I am now free to confess that only 

 short-sighted judgment led to its selection for the plate. No 

 difference between the cells other than size is discernible. 



