HuBER, Sensory Netve-fibers in Visceral Nen>cs. 149 



non-medullated, form plexuses with smaller meshes, to which 

 also the non-medullated collateral branches contribute. This 

 plexus is also in the mucosa, more superficial than the primary- 

 plexus above mentioned, and therefore nearer the epithelial lin- 

 ing. The non-medullated terminal and collateral branches end 

 in arborizations, many of the terminal branches of which pass 

 into the epithelium to terminate between the epithelial cells. 



Before closing I wish to mention briefly some sensory nerve 

 endings, which I believe, should be regarded as the termina- 

 tions of sensory nerves of the sympathetic; these are, however, 

 not confined to the viscera. 



Dogiel (18) has described sensory nerve endings in the ad- 

 ventitia of arteries and veins of the pericardium, also in the 

 vessels of the central tendon of the diaphragm, gall bladder 

 and the capsule of the kidney. At his suggestion Schemetkin 

 examined the larger vessels with reference to this point and 

 found sensory nerve endings both in the intima and adventitia, 

 especially in the former, in the arch of the aorta and pulmonary 

 arteries. Dogiel states that there seems to be no doubt that 

 the sensory nerve endings found by himself and Schemetkin are 

 found not only in the wall of the above mentioned vessels, but 

 are characteristic of all vessels. The writer (29) has described 

 sensory nerve endings in the adventitia of the vessels of the 

 pia mater. I have further observed them in the adventitia of 

 vessels in the thyroid gland in several methylen blue prepara- 

 tions prepared by my assistant, Dr. DeWitt. Also in other 

 locations, though not so clearly as in the vessels of the pia 

 mater. 



It has occurred to me that the human uterus, with its large 

 vessels and blood spaces might with profit be studied with refer- 

 ence to the question of the presence of sensory nerve endings 

 in their connective tissue coats, as it seems to me not all the 

 large medullated fibers going to this organ are accounted for by 

 those which terminate in the mucosa and the epithelial Hning. 



