Huber-DeWitt, N euro -tendinous End-organs. 195 



ing the most varied form of enlargement, some broad and un- 

 gainly, resting directly on the nerve trunk, sometimes simply 

 rectangular processes, but oftener other bits or masses of granu- 

 lar matter, sharp and pointed or oval or irregular, are attached 

 to it in all conceivable ways and places, making an indescribably 

 irregular ending. Some of these side processes twine them- 

 selves about or enclasp the fasciculus, while others are simply 

 spread out upon it, the whole ending resembling somewhat a 

 long, climbing vine, with broad, strong tendrils, enclasping the 

 fasciculus against which the vine rests, and bearing leaves and 

 flowers of the most fantastic patterns to adorn its surface. We 

 have represented in Plate XVI, Fig. 20, a typical end-organ 

 taken from a dog, which had been injected with methylen-blue, 

 the tissues fixed in ammonium molybdate, dehydrated, and 

 cleared and teased in xylol and mounted in balsam. In this 

 method, there is no softening of tissues and all the parts bear 

 their normal relation to each other. 



In the neuro-tendinous end-organ of the cat, the main stem 

 of the nerve usually forms a much less prominent part of the 

 picture, the finer medullated branches, with their still finer non- 

 medullated divisions and the terminations with their graceful 

 curves and fanciful twining tend to cover and conceal the 

 straight rude, ungraceful outline of the large trunk, which in 

 the end-organ just described, formed such a prominent part of 

 the ending. In Plate XVI, Fig. 21, is shown, however, an end- 

 organ from the cat, in which the large medullated nerve, nearly 

 unbranched, occupied the greater part of the equatorial region 

 of the organ. Usually the large nerve branches and rebranches, 

 bush-like, the branches becoming finer and finer, finally losing 

 their sheath of myelin, and as axis cylinders, further divide and 

 twine in long, graceful curves, and become beset with enlarge- 

 ments of the most varied size and form ; some in long strings, 

 like strings of beads, the enlargements small, granular and 

 mostly round or oval and connected by the fine axis cylinders, 

 these simply lying on the surface of the tendon fasciculus or 

 twining in undulating curves about it or between adjacent fasci- 

 culi and sometimes sending off larger processes which partially 



