200 Journal of Comparative Neurology. 



Relation to other sensory endings. — Golgi and Cattaneo both 

 mentioned the intimate relation existing sometimes between the 

 neuro tendinous end-organs and certain small sensory endings 

 resembling small rudimentary Pacinian corpuscles and usually 

 spoken of as Golgi-Mazzoni organs. Ciaccio also refers briefly 

 to this fact and Ruffini has dwelt upon it with considerable em- 

 phasis in each of the series of three papers before alluded to. 

 In our preparations, we have observed neuro-tendinous end- 

 organs in close proximity to large Pacinian corpuscles, to small 

 Pacinian or Golgi-Mazzoni organs, to Krause's cylindrical and 

 spherical end-bulbs, and to neuro-muscular spindles. Some of 

 these preparations deserve a little fuller mention. In one prepara- 

 tion, two medullated nerves separated themselves from the main 

 trunk and ran together for a considerable distance. One of 

 these finally left the other and divided into two branches, one 

 of which bore at its extremity a large spherical end-bulb of 

 Krause. The other branch divided, each subdivision innervat- 

 ing a cylindrical end-bulb of Krause, in close proximity to a 

 large neuro-tendinous end-organ, which was supplied by the 

 nerve which had accompanied that supplying the three Krause 

 end-bulbs. In the same preparation and almost in the same 

 field of the microscope was a neuro-muscular spindle, having an 

 independent nerve supply. 



We have often seen neuro-tendinous end-organs and neuro- 

 muscular spindles in close proximity, sometimes lying side by 

 side, oftener end to end, and often enclosed in the same connec- 

 tive tissue capsule. In most cases noted, however, the two end- 

 organs have had an independent nerve supply no matter how 

 closely related they might seem to be ; or if the nerve supply 

 has not been independent, it has been difficult to demonstrate 

 the contrary fact. In one particularly fortunate preparation, 

 however, we were able to see a neuro-muscular spindle and a 

 neuro-tendinous end-organ, lying end to end, in the same cap- 

 sule, where it seemed to us that one medullated nerve fiber ran 

 along beside them sending off fibers at right angles to itself to 

 innervate the neuro-muscular spindle and then at the other ex- 

 tremity of the capsule, a nerve was given off which supplied 



