384 Journal of Comparative Neurology. 



tine, one of the dendrites of these cells may be longer than the 

 others and even extend through a nerve trunk to another gan- 

 glion. The neuraxis of this kind of cell is long and extends 

 out into one of the nerve trunks leading from the ganglion, 

 usually as a non-medullated (Remak's) fiber ; it may often be 

 traced, with no or very little branching, till it leaves the nerve 

 trunk and enters into the formation of the intramuscular plex- 

 uses, surrounding and supplying the non-striped muscles of the 

 muscular coat and to some extent also of the muscularis mu- 

 cosae. Although it has been shown by Kolliker (27 and 28), 

 Dogiel (10) and others that the neuraxes of sympathetic neu- 

 rones may possess a thin medullary sheath, it has seemed to me 

 that most, at least, of the neuraxes of the neurones whose cell 

 bodies constitute the ganglia of the intermuscular plexus of 

 the oesophagus, were non-medullated throughout their course. 

 This observation corroborates one made by Huber (20), who 

 says that he believes that the neuraxes of the cells of the 

 peripheral ganglia, — those of the heart, salivary glands, intes- 

 tine, bladder, etc. — are non-medullated throughout. The end- 

 ings of these neuraxes are as described for the nerve endings 

 in non-striated muscle of other parts of the body, the terminal 

 branch dividing into two or three short twigs which end in an 

 enlargement on the non-striated muscle cell (Huber and DeWitt 

 (26) ). While the arrangement of the muscular plexus is usu- 

 ally so complicated that it is impossible to trace a single neur- 

 axis from the cell body where it originates to its termination on 

 a muscle cell, yet I have occasionally seen a fiber which had a 

 shorter course. In these cases, the fiber could, without diffi- 

 culty, be traced from the cell body, leaving the ganglion, often 

 without forming part of a nerve trunk, but passing independ- 

 ently to a muscle fiber in the vicinity of the ganglion. While 

 most of the neuraxes of the sympathetic cells of the intermus- 

 cular plexus of the cesophagus end on the non-striated muscle 

 cells of the muscular walls of the oesophagus, I have at times, 

 as I believed, been able to trace certain neuraxes to the walls 

 of the blood vessels, where they helped to form the vascular 

 plex us of vaso-motor nerves. . s this observation, however. 



