400 GA ULE. [Vol. \' 1 1 1 . 



V. The cytozoa described by Gaiilc in " Uebcr die Bezieh- 

 iing der Cytozoen zu den Zcllkerncn " ^ and in his Strassburg 

 lecture,^ also play an important part in the life-cycle of the 

 spleen. 



VL Cell division was observed in the endothetial cells, in 

 the follicle cells and rarely in amoebocytes. There is a great 

 difference in the character of the caryokinetic threads in the 

 various spleens. I gained the impression that the threads 

 were finer and more homogeneous in the spleens of the 

 tcmporaria than in those of esadenta. The threads of cscii- 

 leiita figures of cell-division were often composed of tiny 

 granules. The color of the tcmporaria figures varied from red 

 to violet. 



VII. The proportion of the protoplasm to the nuclear sub- 

 stance is a further element of variation and is characteristic of 

 the two species. The protoplasm of the tcmporaria spleen 

 stains more intensely with nigrosin than the protoplasm of the 

 esctdenta spleen. 



VIII. Even the nuclei present an entirely different appear- 

 ance at different seasons. The size of the nucleoli, their 

 affinity for color, their tendency to wander out of the nucleus 

 and even out of the cell, changes the whole aspect of the micro- 

 scopic picture. Curves were made of the nucleoli called 

 plasmosoma as to a certain extent typical of these changes. 

 The nuclei as a whole vary greatly in size and in the tints of 

 their main substance. 



Other elements occurring at rare intervals, and not further 

 investigated, were tiny spheres and crystal-like bodies, lying 

 in the blood-vessels and capillaries, and colored homogeneously 

 with eosin. Fragments of red blood corpuscles, undeveloped 

 corpuscles, and megalocytes were also too superficially investi- 

 gated to be especially described here. 



^ Archiv fiir Anatomie und Physiologie, iSSi. 



2 Ueber die Bedeutung der Cytozoen fiir die Natur der thierischen Zellen. 

 58. Versammlung deutscher Naturforscher und Aerzte in Strassburg. Tageblatt 

 18-23. September 1S85. 



