THE FINER STRUCTURE OF THE GLANDULA SUBMAXIL- 
LARIS OF THE RABBIT. 
BY 
BENSON A. COHOE. 
From the Hull Laboratory of Anatomy, University of Chicago. 
WITH 6 FIGURES. 
Since the early researches of Boll, 69, the glandula submaxillaris of 
the rabbit has been the subject of many investigations on the part of 
histologists. This observer believed that the gland might well be re- 
garded as the type of a whole important series of glands, formed on 
the same plan. The character of the cell, with its polygonal form, 
prominent nucleus and abundant cytoplasm, which after treatment with 
osmic acid became dark and granular, led him to consider it a pure 
serous gland. Later observers, notable among whom were Nussbaum, 
Langley, and Miiller, were able to confirm his opinion as to the pure 
serous nature of the gland, and noted in addition that certain of. the 
cells were loaded with granules, while others possessed a clear cytoplasm 
free from granulation. The weight of opinion was that these cells, 
unlike as to their cell contents, simply represented different physiological 
phases of one type of cell. The evidence presented so far. to substantiate 
this view has not been altogether convincing, and in order to test the 
validity of such an opinion, a considerable number of glands, both in 
normal resting conditions and in various stages of activity has been 
studied during the present investigation in order to establish the identity 
or otherwise, the specificity of the different cells in this gland. 
HISTORICAL. 
The minute anatomy of the gl. submaxillaris of the rabbit was studied 
by Erik Miller, 96, in a series of investigation upon the relation of 
gland structure to physiological activity. He found that after sublimate 
fixation and staining with Heidenhain’s iron hematoxylin, alternating 
transparent and darkly stained areas of gland tubules could readily be 
distinguished even with low magnification. By careful technique and 
AMERICAN JOURNAL OF ANATOMY.—VOL. VI. 
