214 Gastric Glands of Dog after Gastroenterostomy 
Bensley and Zimmermann did not find them, and my own observations 
have been quite in accord with theirs. No chief cells appear in any of 
my preparations made by the methods introduced by Bensley, which are 
not either clearly mucous or clearly ferment cells. 
While the body chief cells are almost exclusively ferment cells, there 
exist among them occasional though rare mucous cells. Somewhat similar 
cells described by Trinkler, 83, were interpreted by him as transition 
forms between parietal and chief cells, but as Bensley has pointed out, the 
selective action of mucicarmine demonstrates clearly their true nature. 
III. The pyloric region is occupied by mucous membrane, which is 
whitish yellow in color. It extended in several dogs to a distance of 6 to 
8 cm. from the pyloric valve, the extent being usually about 1 cm. 
greater along the major curvature than along the minor. ‘These measure- 
ments agree with those reported by Deimler, 04, for the same animal. 
When long strips of mucous membrane extending from the pyloric valve 
into the fundus region are removed from the stomachs of dogs and 
flattened out, the distance from the pyloric valve to undoubted fundus 
mucosa is from 10 to12 cm. An intermediate zone 2 to 3 cm. wide exists 
between the two regions. In the pyloric region the foveole are wider 
than in the fundus region and each extends through from one-third 
to two-thirds of the thickness of the mucous membrane and each, as has 
been shown by the reconstructions of DeWitt, receives the openings of 
several branched glands. These have a larger lumen than the fundus 
glands, and are lined by cells of one kind only which resemble 
accurately the neck chief cells. Like them they secrete mucus accu- 
mulating during rest in spherules in the free end of the cell, flattening 
the nucleus against the attached end and being poured out after inges- 
tion of food. It occupies the meshes of a delicate cytoplasmic framework. 
There appear among these cells, as Hamburger, 89, has pointed out, the 
small pointed cells of Stohr which Bensley found also among the neck 
chief cells of the fundus region. Stéhr, 82, describes also the occasional 
presence of parietal cells in the pyloric glands of man. I did not find 
them in my preparations of the dog’s stomach. 
In the intermediate zone, as one studies parts successively nearer the 
pylorus, the parietal and ferment cells gradually become fewer and 
disappear. The disappearance of the two kinds of cells seems to pro- 
ceed pari passu, and I did not find the parietal cells extending more 
than one or two glands beyond those in which ferment cells are to be 
found. Across this zone the gland bodies become progressively shorter 
