Basil C. H. Harvey 215 
till they disappear, while the length of the gland necks is very little 
altered. From a study of the intermediate zone it appears that the 
pyloric glands correspond to the neck region of the fundus gland without 
the parietal cells. 
Capr’s EXPERIMENTS AND OBSERVATIONS. 
In 1901, in a paper dealing with the normal anatomy of the gastric 
mucous membrane, and with the changes which it undergoes in various 
physiological conditions and after its subjection to various operative 
procedures, Cade gives an account of the alterations in its structure in a 
dog and a cat near the site of gastroenterosomies which he had performed. 
His observations were made on only one animal of each species and 
the changes were studied between six and seven months after the opera- 
tion. In the dog he effected a gastrojejunostomy connecting with the 
stomach in the fundus region, by which part of the food might pass 
into the intestine, but since the normal pylorus remained open, part 
of the food might pass by the normal way. In the cat he made a 
similar anastomosis, and in addition divided the mucous membrane in 
the middle of the stomach, making two sacs, one proximal communicating 
with the cesophagus and jejunum, and the other distal communicating 
by way of the pylorus with the duodenum but never containing any food. 
The animals were killed after six and a half months and the changes 
at the site of the gastroenterostomies studied. 
He found the foveole at the wound margin enlarged and deepened, 
due to the absorption into them of parts of the gland necks. In their 
deeper parts were seen occasionally cyst-like dilatations, the walls of 
which were made up of cells shorter and flatter than those normally 
constituting this epithelium. Otherwise they were unchanged. 
The glands were sinuous in outline and their lumina irregularly en- 
larged. The gland cells were of one kind only and resembled closely 
the neck chief cells of normal glands. They were cylindrical or cubical 
in outline, with nuclei poor in chromatin and often flattened against 
the attached ends of the cells. The cytoplasm was formed of a network, 
with fine meshes and stained a light pink tint with carbol-thionin, similar 
to, but fainter than that which he observed with this dye in pyloric 
gland cells and other undoubtedly mucous cells. They did not, how- 
ever, take the metachromatic pink tint with toluidine blue which he 
obtained in clearly mucous cells. They did not take any stain at all in 
muchematein, mucicarmine, or indulin, but did not differ in this respect 
from normal neck chief cells or pyloric gland cells, for Cade did not 
