Herrick, Pathology of General Pa}alysis. 159 



tion. Both are figures of actual sections from which Figs, j 

 and 4. were drawn. 



THE CEREBELLUM. 



The cerebellum, although somewhat isolated from the real 

 centre of morbid activity, might be expected to be involved 

 with other portions of the brain. The vessels of the meninges 

 are only slightly modified and the intrinsic capillaries not at all. 

 The only way in which the extensive changes in the basal gang- 

 lia of the fore-brain could react indirectly on the cerebellar 

 structures would seem to be through an atrophy of disuse. 

 While the ganglia in the motor tracts bear unmistakable evi- 

 dence of extreme degeneration it would seem quite improbable 

 that an extensive atrophy should have had time to develop itself. 

 It will be remembered that (ijx our view) the axis cylinders of 

 the Purkinje cells passes directly into the restiformia, while the 

 peripheral or protoplasmic processes afford opportunity for asso- 

 ciation by contiguity with the fibres of the mid-peduncles of the 

 cerebellum which on their part may connect with the cells of the 

 basal ganglia. 



Since, then, the relations are very indirect, we should not 

 be surprised to find the cerebellum normal in the absence of irri- 

 tating causes in the organ itself. The cerebellum can hardly be 

 subject to as rapid alterations in blood pressure as the cerebrum 

 and contains within itself a large stock of reserve nutrient ma- 

 terial. Careful examination reveals only a few cases where the 

 cells of Purkinje have some traces of the fatty degeneration 

 seen elsewhere {Fig. 5, Plate C.) Most of the lobules are nor- 

 mal, but occasionally there is one of the folia in which there is 

 extensive atrophy of the cells of Purkinje. Fig. 4, Plate E, il- 

 lustrates such an instance. In the sections wherein ordinarily a 

 score or more of cells should stand, only one or two isolated cells 

 remain. There is no notable degeneration in the other struc- 

 tures, but the space which should contain these bodies is empty 

 or contains shriveled remnants. In these cases it might appear 

 that the change was the result of early stages of the disease. 



In the unaltered Purkinje's the structure is well preserved 



