Literaty Notices. cxi 



citory areas of the skin. His method is that which he has used so 

 successfully in other areas. 



The mucous membrane in pieces 2x3 cm. or less, were treated on 

 the slide with one-sixteenth per cent methyl blue solution and fixed 

 with a saturated solution of ammonium picrate or mixture of ammoni- 

 um picrate and osmium. In most cases the epithelium was removed 

 carefully from the surface, which latter was arranged on the slide and 

 imbedded in glycerin. After a few days the preparation became per- 

 fectly transparent. Sections from the glans penis were stained and 

 embedded between pith and cut vvith the freezmg microtome. 



Three sorts of end-organs were recognized: i, genital nerve 

 bodies; 2, nervous end organs, (end kolben); and, 3, Meissner's tac- 

 tile, bodies. The differences between these bodies is not an essential 

 one. In all cases the axis cylinder enters the cavity of the bulb and 

 divides into a certain number of varicose branches and threads which, 

 during their course, form a number of spiral turns and anastomose and 

 interblend in the most various manner, and finally form a complicated 

 system of loops and meshwoik. The differences between the several 

 varieties consists chiefly in the details of combination and ramification 

 of these fibres in the cavity of the bulb, The genital bodies are the 

 most complicated of these structures. The Meissner's bodies are 

 next in complexity. All these terminal bodies have this in common 

 that from the nervous apparatus of the body in each type a certain 

 number of fibres are separated, which penetrate the epithelium and 

 end free with knob-like tuberosities. The non-medullated fibres pass 

 to the blood vessels about which they form a close network. Separate 

 nerve bulbs are connected by fine fibres with each other, though each 

 end bulb receives several branches. It would appear that the genital 

 bulbs particularly are combined into a close system. 



Eegeneration of Nerve Fibres.^ 



This paper adds to the long list of ambiguous data and does not 

 include references to the latest literature. We fail to find any recog- 

 nition of the paper by Howell and Huber and other important con- 

 tributions to this difficult subject. 



The nuclei of Schwann's sheath could not be discovered to have 

 any part in the regeneration process. New growths spring from the 

 central tips of the severed fibres and gradually become encased in a 



^ KoLSTER, R. Zur Kenntniss der Regeneration durchschnittener Ner- 

 ven. Archiv.f. mikr. Anat., XLI, 4. 



