cxxxii Journal of Comparative Neurology. 



cure, are liable to relapse; that physicians are more prone to relapse 

 than other niorphinomaniacs. from generally having morphine in their 

 possession and administering it, as well as from the despondency and 

 excitement of their irregular life; that cured morphinomaniacs are less 

 apt to relapse the second than the first time. One physician patient, 

 who became addicted to morphine through having recourse to opiates 

 for the relief of cough, returning home too soon (on the eighth day), 

 relapsed, but made, on a second trial, a permanent cure, after then 

 remaining twenty-seven days. J. H. de Wolff, of Baltimore, ^ gives 

 20 grains of sulphonal for sleep, with auri et sodii chlor. Stephen 

 Lett, of Guelph,- narrates a case of double addiction (morphine and 

 cocaine) whose daily ration -was 60 grains morphin. sulph. and 70 

 grains cocain. hydrochlor. hypodermatically ; and one of laudanum, 

 16 fluid ounces being taken daily. Araenorrhoea and sterility are 

 generally present, these functions resuming vigor on discontinuance 

 of the opiate. J. B. Mattison-' relates the case of a physician's wife, 

 aged 34, who, after 40 grains hypodermatically and one or two 5-grain 

 doses daily by the mouth, advanced to 60 to 75 grains daily of mor- 

 phine by the mouth only, and at one dose. Afterward she resumed 

 the hypodermatic injection of 40 to 50 grains a day. Three women, 

 dismissed cured, each took 30 grains daily for years Two were 

 sisters; one had indulged for ten, the other for seventeen years. Ad- 

 ministered by the skin, the narcotic action is double of that by mouth. 

 He has generally found female morphinomaniacs neat and tidy. One 

 laudanum-taker of twenty-two years' standing had reached nearly a 

 pint a day. J. B. Mattison, of Brooklyn,"* attributes nearly all his 

 cases of narcotic inebriety to the medical prescription of the drug, in 

 the first instance ; though he recognizes the peculiar narcotic status, 

 ancestral and acquired. It should be made felony for retail drujigists 

 to sell morphine, chloral, or cocaine, or to repeat a prescription con- 

 taining either drug, except on order of a physician. 



Tobacco. — Francis Dowling, of Cincinnati,''' dwells on the influ- 

 ence of tobacco in causing amaurosis. He found in 3,000 tobacco 

 workers in Cincinnati, 150 with impaired vision. A woman of 40 



'^Medical Brief, March, 1S93. 



^ Times and Register, October iS, 1893. 



^ Ibid, October 22, 1892. 



* Weekly Med. Review, St. Louis, February 11, 1893. 



'^Medical and Stirgieal Reporter, October 22, 1892. 



