398 E. R. Dowxninc. 
strands disappear except one continuous strand which connects all 
the microsomes, or better now termed the chromomeres. Of these 
there are probably forty-eight. They gradually disappear and the 
entire thread becomes smooth and takes nuclear stain with great 
intensity. It fragments into twelve segments, which come to lie in 
the equatorial plane, the point of the V directed toward the cells 
center. Centrosomes appear at the poles. Spindle fibres stretch from 
the tips of the V’s to the centrosomes. 
Metaphase. 
The division of the chromosomes is longitudinal beginning with 
the tip. The open arms of the V’s remain united temporarily and 
as they separate they are connected by fibres. 
Anaphase. 
The daughter chromosomes are V-shaped. As they approach 
the pole their tips fuse as they come into contact and we have 
often a deeply staining mass with the ends of the chromosomes still 
unfused and protruding. The interzonal fibres dissolve apparently. 
If they persist sufficiently long the zwischen Körper may appear as 
the cell contracts to make the daughter cells. 
Telephase. 
The spindle fibres also disappear and the centrosomes. The 
chromosomes fuse ultimately to make the daughter nuclei. The 
nuclear membrane reforms. The chromomeres reappear and become 
connected again by linin threads. These threads decrease in thick- 
ness as they increase in number. The chromomeres are replaced 
by numerous microsomes. ‘The reticulum is re-established by a 
process the reverse of that by which it disappeared in the parent 
cell. The reticulum becomes gradually finely meshed and indistinct. 
The nucleolus reappears, small at first but gradually larger, and the 
daughter cells are in the resting stage. They may grow to the 
size of their parent becoming interstitial cells or remain without 
growth as the spermatogonia of the first generation. Similar telephase 
has been reported by Fremutne and Rast in the epithelial cells of 
amphibia. 
