400 



On opium. 



At 10 minutes before one o'clock, I introduced between 

 tlie fl-;in and mufcles of the left leg (which had had the al- 

 kohol and water injedted into it at the commencement of 

 the experiment) a portion of the aqueous Jolution of the opi- 

 um lailiicce, of the vial A. (experiment 3.) At this time the 

 frog was very lively. Much of the fokition was difchai-ged 

 by the motion of the leg in placing him under a receiver : 

 in 5 minutes he moved about brifkly ; in 10 his left leg be- 

 gan to drag. At this period of the experiment, iomething 

 occurred to carry me away, and I put the frog into the 

 water. 



Experiment 29. 



Auguft 2 1 ft. The frog, the fubjedt of the preceding ex- 

 periment,had perfeftly regained hislivelinefsand animation. 

 At 30 minutes after one o'clock, I injected a few drops of the 

 aqueous folution A. (experiment 3.) into his ftomach. In 3 

 minutes, confiderable contradtions of his abdomen appear- 

 ed, and continued at intervals ; with an opening of the fau- 

 ces, as if to obviate the difficulty of refpiration. By agi- 

 tating him, he was made to move with confiderable brifk- 

 nefs. At 15 minutes before 2, he appeared very lively. I 

 injetled a fecond portion into his ftomach, and a third, at 20 

 minutes after 2, -as he ftill continued very lively. Neither of 

 thefe appeared to afie£t him. At 25 minutes after 3, I in- 

 jefted a portion, through a fmall ineifion, into the abdo- 

 men ; a confiderable part of it was rejedted ; but his lower 

 limbs were paralized to a certain degree in 5 minutes. He 

 could not jump, but drew his legs after him with much 

 difficulty. In 12 minutes he could jump flightly. At 

 45 minutes after 3, 1 injedted more, and retained it by keep- 

 ing him upon his back. At 4 o'clock he jumped pretty 

 well. At 30 minutes paft 4, he continued lively. 1 now put 

 him into the water, but found him dead the following day. 



His 



