On opium. 



403 



it, for at 5 o'clock it beat only 50 weak pulfations in a mi- 

 nute, and at 10 minutes paft 5, only 18, and chiefly of the 

 auricle. A pointed inftrument fcarcely increafed its vi- 

 gour. 



The ftomach was cormgated, and contained the folution 

 mixed with a flimy matter. 



EXPERIMEN T IT^. 



At 15 minutes before 2, P. M. I injected a few drops of 

 the aqueous folution A. into the abdomen of a lively frog, 

 the greateft part of which cfcaped. Though the frog was 

 Jiijiy contradled before the introdudion of the folution ; yet 

 the abdominal mufcles relaxed and elongated themfelves the 

 inftant it was introduced. 



At the expiration of 5 minutes no effed: was produced. 

 At I o minutes being equally lively, I introduced another 

 portion and retained it there for fome time. 



In I o minutes he lay upon his abdomen, not as iifual 

 refting upon his legs. Irritation with a pointed inftrumcnt, 

 did not now caufe his extremities to contrad; ; they appear- 

 ed perfedtly paralized. When placed upon his back, he 

 lay without motion. His eyes were fenfiBle to irritation. 



In 20 minutes he began flowly to move his lower, and 

 foon after his upper extremities, and gradually elevated 

 himfelfupon them as ufual. Contradions were produced 

 by zinc and a filver probe pafled into the abdomen. 



In 5 minutes from this time he appeared to be nearly dead, 

 and was completely fo in two or three minutes longer. At 

 3 o'clock his limbs were nearly ftiff. 



On opening the thorax the heart was beatlhg 60 vigor- 

 ous pulfations in a minute, I removed it from the body, 

 and in 15 minutes it pulfated only 32, and chiefly of the 

 auricle. In 30 minutes after 3, it beat only 10 times. At 

 45 minutes, it was excited to a few weak pulfations by a 

 pointed inftrument. 



3 G a The 



