4o6 O N O P r U M. 



folutlons 0^ common, and of the lettuce o\)\\\m ; I next pro- 

 ceeded to fome few experiments with the fpirituous tine-' 

 turesy A. and B. defcribedin experiments 7 and 8. 



Experiment t,^. 



September ad. At one o'clock, P. M. I injeded between 

 the fkin and mufcles of the right inferior extremity of a 

 lively frog, a few drops of the fpirituous tintTiure of opium 

 laBucce, A. (experiment 7,) and at the fame time, I intro- 

 duced beneath thelkin of the left leg fome of the fpirituous 

 tinfture oicommon opium, B. (experiment 8.) At the mo- 

 ment of introdudion both tindures gave pain, and by the 

 efforts which the frog made to efcape, a confiderable portion 

 of the tindures was loft. In 5 minutes he hopped with 

 great difficulty; or rather, his motions feemedto be perform- 

 ed by quickly and repeatedly pufliing himfelfon by his low- 

 er extremities. Confiderable mflammation was fpeedily 

 induced in both thighs, and blood was even effufed. 



In 10 minutes his motions were more difficult; and his 

 jumps more circumfcribed. Both legs feemed equal- 

 ly affeded. 



A drop of the tindure put upon his eye appeared to give 

 pain, as he immediately clofed it. 



In 20 minutes I injeded a few more drops below the fkin 

 of the inferior extremities. In a few minutes, both legs ap- 

 peared immoveable. In 5 minutes from this time, the in- 

 flammation was feen extending itfelf with confiderable 

 fpeed, down the legs ; as many fmall veffels before invifi- 

 ble to the naked eye, were now diftended with red blood. 

 His legs lay motionlefs in any pofition they were placed; 

 and no irritation, except that produced by zinc and filver, 

 caufed them to move. Thefe metals caufed ftrong con- 

 vulfions in both. 



For 



