292 



The Journal of Heredity 



of the offspring of this original pair, 

 was also used in an experiment in 

 which poison was administered, this 

 time in the form of lead acetate/ He 

 finally died with symptoms of lead 

 poisoning. The ancestry of the fe- 

 male, designated lA (298.1), to which 

 20.2 was bred, is not accurately 

 known, and the same is true of 3A 

 (296.1) and 2A (297.1), which occur 

 on the maternal side of Waltzcr's 

 pedigree. A number of young rab- 

 bits were discarded before being 

 marked with ear tags, and these three 

 were later returned to the breeding 

 pens. There is much reason to be- 

 lieve that they are closely related to 

 one another, possibly even being lit- 

 ter mates, and that they are all de- 

 scended from $ 1 4. 1. This presump- 

 tion is based on color markings and 

 other known facts, but the relation- 

 ship cannot be asserted. 



The mating of 20.2 and lA (298.1) 

 gave rise to 299.3, the father of Waltz- 

 cr, who was, so far as the records 

 show, an entirely normal rabbit, 

 Waltzcr's mother (274.6) was also 

 normal, but her father, 3x\ (296.1), 

 when about half grown acquired a 

 deformity recorded as "probably spinal 

 trouble." Later this seemed to be 

 complicated by other nervous disturb- 

 ances so serious that he was disposed 

 of. The mother of 274.6 was 2A 

 (297.1), which was normal, and con- 

 cerning the ancestry of which there 

 is uncertainty, as has been stated. 



Discussion 



Summarizing Waltzcr's pedigree, 

 then, we find first the possibly sig- 

 nificant fact that his paternal grand- 

 sire and great grandsire were poisoned 

 by drugs reputed to have a deleteri- 

 ous effect on the germ plasm, and 



Chart I. Pedigree of "Waltccr" 



$ 301.3 J 

 "Waltzer" 



^299.3 < 



^20.2 

 (leaded) 



6 14. 1 — original purebred Dutch 

 (alcoholized) 



$15.1 — original purebred Dutch 

 ^9 I A (298.1) — Probably descended from 14.1 



(? 3A (296.1) — Showed deformity, "probably spinal trouble," when 

 about half grown. Later seemed to suffer other nervous complica- 

 ^274.6 -^ tions and was killed. Probably descended from 14. i 



92A (297.1) — Probably descended from 14. i 

 Chart II. Pedigree of Litter 328 



S 299.3 



f S 20.2 



$328.1 



6 328.2 — paralyzed ; killed when 



about 7 months' old 

 9 328.3 

 $328.4 

 6 328.5 

 6 328.6 



* Cole, L. J., and L. J. Bachhuber. "The effect of lead on the germ cells of the male 

 rabbit and fowl as indicated by their progeny." Proc. Expcr. Biol, and Mad., Vol. XII, pp. 

 24-29. 1914. 



