DOCUMENTS 927 
IIl.—Case reported by Robert J. Ashton, M.B., Kaschwa 
Medical Mission, Mirzapur (N.W.P.). 
“A coolie, aged 27, was bitten in the right foot by a cobra at 
5.30 a.m., on September 16, 1900. Half an hour later 10 c.c. of 
antivenomous serum were injected subeutaneously into the left 
forearm. The patient experienced great pain in the foot, torpor, 
and great weakness. Recovery, without complications.” 
III.—Case reported by Dr. Simond (Saigon). 
“Nouyen-Van-Trane, an Annamese, aged 25, employed in the 
Botanical Gardens at Saigon, was bitten at 10:30 arn son 
March 11, 1899, by a cobra which had escaped from its cage. The 
bite was inflicted on the palmar surface of the index finger of the 
right hand, and the fangs had penetra‘cd deeply. 
“ This native, to whom a sensible comrade had applied: a ligature 
round the wrist, was brought to the Pasteur Institute three hours 
later. He was drowsy, with drooping eyelids; his speech was 
difficult and almost unintelligible. Deglutition was impossible, 
and ingurgitated liquids caused vomiting. ‘The hand was greatly 
swollen at the seat of the bite, and the cedema extended to the 
forearm. There was partial anesthesia of the skin. As soon as 
the patient arrived, I gave a single injection, beneath the skin of 
the flank, of three doses of serum, that is, 30 c.c. In the evening 
I again injected 10 c.c. of serum. At 10 p.m. the general condition 
of the patient seemed to be improving. Next morning he was less 
depressed, spoke more easily, and was able to swallow. Convales- 
cence began from this moment; the cedema and numbness of the 
hand and arm, however, persisted for several days. 
“ Recovery was complete on March 20. I have no doubt that 
in this very serious case the antivenomous serum preserved the life 
of the patient, since his condition was desperate when I saw him. 
“This is the second instance within four months of the success- 
ful treatment of snake-bites at Saigon by Calmette’s serum. In the 
former case two natives were bitten by the same animal. One of 
them, who permitted the injection of serum, which was performed 
