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His pulse and respiration began to increase in frequency, and the 
pulse became very compressible, but quite regular. After the first 
injection of serum his temperature was 98° F., pulse full, high 
tension, regular, 88, and respirations greatly increased in frequency. 
He now became very drowsy, and had to be roused when the second 
Injection of serum was given. Soon after this the patient’s general 
condition and pulse improved. . . . He had complete loss of 
sensation in the bitten finger, in the part terminal to the site of 
the puncture, for some days. . . . The injection of Calmette’s 
serum gave rise to no local reaction, and caused no pain. It did 
not affect the temperature, but was followed in half an hour by 
perspiration, which was very profuse four hours after the injection. 
The patient made a complete recovery. . . . The 
serum used in this case was fresh, having been prepared at Lille 
etJuly LOO | 
VIII.—Note of case treated by Major Rennie, R.A.M.C., trans- 
mitted by M. Klobukowski, French Consul-General at Calcutta, 
September 5, 1899 :— 
‘ A remarkable cure effected by Major Rennie, by means of 
Calmette’s method, has just taken place at Meerut. Since the 
introduction of this remedy three years ago, its efficacy has been 
abundantly proved, but the present case is especially interesting, 
since it seems to show that the serum can be successfully employed 
even in cases apparently desperate. The well-known symptoms 
of poisoning by cobra-venom were already so advanced that the 
patient, who was insensible, was kept alive by artificial respiration 
in order to give time for the serum to be absorbed and to take effect. 
“The truth of the above statements is attested by six doctors, 
and is also vouched for by the Commissioner and Magistrate of 
the military cantonment, who, although not medical men, have, 
nevertheless, had long experience of Indian matters.” 
IX.—Case recorded by Binode Bihari Ghosal, Assistant-Surgeon, 
Jangipur (‘ A Case of Snake-bite [Cobra ?].—Recovery,” Indian 
Medical Gazette, January, 1905, p. 18). 
