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asked me to give him a second injection. This I gave him at 
2.25 p.m. (5 c.c.). 
“Date on bottle used, May 8, 1900. 
“The pains in the joints had disappeared on the second injection 
(which was given in opposite flank). At 5 o’clock the man walked 
away with assistance. He was quite well a couple of hours 
after the second injection, and when I saw him again on May 8 
he was in perfect health.” 
G.—European Vipers (Pelias berus and Vipera aspis). 
XX.—Case published by Dr. Marchand, of des Montils, Loir-et- 
Cher (Anjou médical, August, 1897). 
“ About 11 a.m., on Friday, July 23, Jules Bellier, aged 26, was 
mowing in a damp spot, when he was bitten in the heel by a large 
viper (Vipera berus). The bite, which was deep, was situated on 
the outside of the foot, 1 cm. behind the malleolus and 3 cm. above 
the plantar margin; at this point there were two punctures in the 
skin, 1 cm. apart. Directly after the accident the patient left his 
work, tied his hankerchief tightly round the lower third of his leg, 
made the wound bleed, and came to me with all speed, hopping on 
one foot for about a kilometre. When I saw him scarcely twenty 
minutes had elapsed since the accident ; his general appearance was 
altered, and his pulse rapid. The patient had vomited twice; he 
complained of pains in the head, and of general weakness, and 
‘was afraid,’ he said, ‘of fainting.’ The foot and leg were painful 
under pressure; a slight tumefaction was visible in the peri- 
malleolar region, around the bites, which bled a little. Forthwith, 
after washing the wound freely with a solution of permanganate 
of potash, I injected 10 c.c. of Calmette’s serum into the antero- 
external region of the middle part of the thigh; then I enveloped 
the les in a damp antiseptic dressing as high as the knee. The 
patient breathed more freely and plucked up his spirits. After 
lying down for quarter of an hour he went home on foot (he lives a 
hundred yards from my house). 
