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“The treatment prescribed in Dr. Calmette’s directions was then 
strictly followed. With the usual antiseptic precautions, I made 
several hypodermic injections of the solution of hypochlorite of 
calcium round the bite, and injected the dose of serum indicated 
in two places in the abdominal wall. The patient was then 
vigorously rubbed and covered with woollen blankets. He was 
made to take two cups of a strong infusion of black coffee. Since 
he could not be induced to go to hospital, he was carried half an 
hour later to his home, where he placed himself in the hands of 
a ‘ dresser.’ 
“According to information furnished by Captain Martin, who 
lived on the spot and was able to follow the course of the case, 
the patient remained throughout the day in a state of profound 
prostration, and had several attacks of syncope. The injured limb 
was greatly swollen, and the swelling, which extended to above 
the knee, produced a mechanical difficulty in using the joint, 
leading to a belief that paralysis was setting in. During the 
first five days the condition of the patient was so alarming as 
to cause a fatal issue to be apprehended. By degrees these 
symptoms diminished, until they disappeared about the fifth day. 
“On the twentieth day, C. returned to his work. I saw him 
again a month later, when he was in perfect health; his leg had 
returned to its normal size, and all that remained were two small 
fibrous nodules showing where the bite had been inflicted.” 
XXXV.—Case reported by Dr. Gries, Fort-de-France, Mar- 
tinique. 
“On June 21, 1896, a young black, who had just been bitten in 
the foot by a Bothrops of large size, was brought to the Fort-de- 
France Hospital. The entire limb was swollen and benumbed. 
“Two hours after the accident I gave an injection of 10 c.c. of 
serum in the abdomen, and the patient was taken back to his 
family. I saw him again ten days later, and found that he was 
quite cured. His friends stated that recovery had taken place 
much more quickly than could have been hoped after so serious 
a bite, and without the usual complications.” 
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