140 ON THE EFFECT OF VARIOUS SUBSTANCES IN 



4.28 P.M. Apparently dead. Heart still beating one hour and 

 two minutes after injection of poison. 



The blood, after death, formed affirm coagulum. 



Intestines much congested. Patch of congestion in stomach. 

 Eed serum effused into the peritoneal cavity. 



No local symptoms or changes. 



A good deal of food in the stomach, notwithstanding the 

 vomiting. Digestion was in full action. 



In these and other experiments the dose of cobra-poison was 

 regulated according to the weight of the animal, the same 

 proportion per pound weight being given in each case. 



Experiment III. ' 



A grey cat, 4 lbs. weight, had 20 milligrammes of cobra-poison, 

 dissolved in 1 c.c. of distilled water, injected under skin of flank 

 at 3.39 P.M. of February 25th. 



At 3,40 P.M. a solution of chloride of platinum injected at the 

 same spot. 



3.42 P.M. Very restless. 



3.43 „ Drinks water. 

 3.52 „ Vomiting. 



3.55 „ Dull and depressed. 



4.10 „ Same condition. 



4.20 „ Sluggish. 



4.30 „ Eestless. Moving about. 



4.45 „ Staggers. Getting very sluggish. Walks with 

 difficulty. Head drooping. 



4.54 P.M. Shivering. Head fallen over. 



5 P.M. Fallen over. Slow paralysis creeping over limbs. 

 Eespiration slow. Gets up, rolls over again. On touching the 

 eye the eyelid moves. Eeflex not gone from the ear. 



5.6 P.M. Fallen over. Paralysed. Eeflex nearly gone, still 

 slight from ear. Pupils dilated. 



5.9 P.M. Convulsions. Pupils become normal again. Eespira- 

 tion very slow — 13 per minute. 



5.20 P.M. Tries to rise. Very feebly. 



5.22 „ Fallen quite over. 



