142 ON THE EFFECT OF VAEIOUS SUBSTANCES IN 



3.52 P.M. Crouching; does not appear affected, but is weak in 

 the hind legs when he runs. 



4.10 P.M. Very little affected ; hind legs weaker, but he is 

 very active otherwise. 



4,20 P.M. Much the same ; active, except that hind legs seem 

 rather weak. 



4.55 P.M. Eemains the same. Eecovered perfectly without 

 any further symptoms. 



In order to make sure that the dose of cobra-poison would 

 certainly prove fatal if administered alone, the animal, after its 

 recovery, was injected with a quantity of pure cobra-poison, 

 fifteen times less than that from which it had recovered, and, 

 as will be seen from Experiment VI, death rapidly occurred. 



Experiment VI. 



March 14th. — White guinea-pig that recovered from 30 milli- 

 grammes of cobi'a-poison, mixed with chloride of gold. 



At 4.45 P.M., 2 milligrammes of cobra-poison were injected 

 into the hip. 



4.50 P.M. Very restless ; scratching his skin. 



4.52 „ Twitching; very restless. 



4.59 „ Squeaking ; very restless. 



5.10 „ Injected leg weak ; not so restless. 



5.15 „ Trying to vomit; twitching movement of head, 

 jerking upwards; violent efforts to vomit; a sort of cough; 

 flows from nostrils and mouth ; getting gradually paralysed, he 

 still crawls ; nearly violent efforts to vomit. 



5.24 P.M. The animal creeps along, putting his head along the 

 ground. 



5.26 P.M. Apparently dead ; heart still beats. 



At 4.45 P.M. the injection was made, and at 5.26 p.m. the 

 animal was dead. Death in 41 minutes. 



Experiment VII shows that chloride of gold is a chemical, 

 and not a physiological antidote, and does not prevent the 

 action of the poison after its absorption. 



