126 NEW YORK ZOOLOGICAL SOCIETY. 
pears to have resulted, I infer that the growth of these bacteria 
has been mostly, if not entirely, post mortem, and that it has 
nothing to do with the explanation of the disease. 
Vessels.—Many of the vessels of the cord show the presence of 
these bacteria in numbers equal to those found in the membranes, 
otherwise the vessels are normal, excepting in certain gliomatous 
areas in the posterior column, where many of them exhibit thick 
and sclerosed walls; in other parts of the cord atheroma and end- 
arteritis are entirely wanting. 
Cord.—No marked pathological lesions are evident in the upper 
portion of the cord (cervical and upper dorsal) and in no parts are 
evidences of acute myelitis or softening found. In the lower dor- 
sal and in the lumbar portions of the cord and, to a much less 
degree, in the sacral portion, a V-shaped area is found which im- 
pinges near to, but not entirely on, the peripheral fibers and ex- 
tends toward the center of the cord to within from .1 to .3 cm. 
of the gray commissure. In this area a marked proliferation of 
glia is shown mingled with connective tissue hyperplasia and re- 
sulting in the formation of a firm mass of tissue in which vessels 
with greatly thickened walls are found. But few nerve fibers are 
still remaining in this zone. 
This sclerosis chiefly involves the column of Goll. The general 
character of the lesion resembles that seen in disseminated scle- 
rosis. 
Gray Matter.—No gross changes are present in the gray mat- 
ter. The vessels are aodeete injected and there is slight dila- 
tion of the lymphatics and of the perilymph spaces. 
Since the cord was not placed in fixing fluid for some hours 
after death, the cytoplasmic findings are not to be absolutely re- 
lied upon. The technic employed for this purpose was that of 
Neisl. 
The cell groups are larger and contain more cells than in the 
human, but the general arrangement of them is as in man, and the 
ventro-lateral and the ventro-mesial seem to be the most prominent 
collections of the anterior horns. It is difficult to make out a 
definite arrangement in the posterior horns. The cytoplasmic 
alterations are about equally present at all the levels and possess 
the same general characteristic throughout. The majority of the 
cells are normal, in so far as we may judge from the results 
of the Neisl method. The most frequent alteration in the plaques 
is a coarsely granular disintegration of the chromatic bodies with 
a chromatophilia of the remaining plaques. Sometimes the frag- 
mentation is final, and a few cells show chromatolysis, but the 
above is the most frequent lesion, and, inasmuch as it is most pro- 
