NINTH ANNUAL REPORT, 163 
nective tissue. The vessels of the membranes show a general con- 
gestion and a few minute haemorrhages are present, but no cellu- 
lar exudation or other evidence of acute inflammatory processes 
is present, except for a considerable amount of clear serous effu- 
sion between the membranes. The walls of the meningeal ves- 
sels, in some cases, show a moderate degree of hyaline degenera- 
tion. 
Cervical Cord—The general structure shows no change but 
the lymphatic spaces are much distended, particularly about the 
vessels and the larger ganglion cells. The blood vessels show a 
very general periarteritis, the hyperplastic tissue of the adventitia 
being highly cellular. The intima in most instances is also thick- 
ened and a few of the vessels show proliferation of the endo- 
thelium. Occasional areas of granular necrosis are present, most 
commonly about the larger lymph spaces and affecting both gray 
and white matter. The ganglion cells of the anterior horns show 
degenerative alterations, the most frequent of which is eccen- 
tricity of the nucleus with granular degeneration of the cytoplasm. 
Other cells appear perfectly normal, while some are atrophied 
and distorted. A good many cells contain many perinuclear gran- 
ules which stain black with osmic acid. Sections prepared by the 
osmic acid method show degenerated fibers in large numbers in 
the posterior columns, mostly in the column of Goll, in the per- 
ipheral portions of the lateral columns and in small numbers in 
the cross pyramidal, direct pyramidal and the anterior ground 
bundle. Degenerated fibers are also demonstrable in the pos- 
terior nerve roots in very small numbers, but none can be found 
in the anterior nerve roots in these levels. 
Dorsal Cord.—The alterations are like those of the cervical 
cord, but the degenerated fibers occupy a relatively larger part 
of the posterior columns and the anterior and lateral portions of 
these levels are much less affected, while the degenerated fibers 
are more widely separated. 
Lumbar and Sacral Cord.—Changes like those described above 
are present throughout, but relatively fewer fibers are degenerated, 
and those found are chiefly demonstrable in the lateral columns 
and in the outer parts of the posterior tracts. 
Bone.—Body of dorsal vertebra. The block required but very 
sight decalcification and could be easily cut with an ordinary 
scalpel before this was done. 
The periostium shows a general thickening in adult fibers and 
the connective tissue cells are abnormally numerous, but it does 
not present the picture of an active proliferative process. No 
