164 NEW YORK ZOOLOGICAL SOCIETY. 
osteoclasts could be demonstrated and the osteogenitic layer of 
the periostium cannot be clearly differentiated. 
The compact portions of the bone are made up of a frail net- 
work of thin plates and spicules, and in many of these narrow 
septs the Haversian canal is occupied by tissue similar to that to 
be described as occupying the cancellous crypts. These spaces 
are filled, to the exclusion of fat, by a dense mass of cells, the 
integers of which are for the greater part mononuclear cells re- 
sembling lymphocytes; with these are associated polynuclear leu- 
cocytes, among which eosinophiles are very common; red blood 
cells, largely nucleated ; plasma cells and large polymorphous cells 
which have long slender processes that apparently make up the 
chief framework of the tissue. The endostium is entirely want- 
ing in many places; in a few others it is represented by a nearly 
normal, though highly cellular membrane, but, as a rule, the cal- 
careous tissue changes directly into the marrow pulp or to a layer 
of large cubical, or polygonal, cells, among which are frequent 
larger polynuclear osteoclasts (plate 5, Fig. A). Thin walled 
blood vessels are very numerous in the cellular pulp, and blood 
cells, both nucleated and nonnucleated, are scattered throughout: 
In a good many areas masses of brown pigment are found, evi- 
dently resulting from the breaking down of blood. Giant cells 
are very numerous throughout this pulp and the cytoplasm of 
some of them appear to contain calcareous granules. The gen- 
eral appearance of this pulp, the stoma of which is very scant, 
resembles almost identically a giant celled sarcoma. 
CASE: 
Macaque (Macacus cynomolgus ).—This was a mildly progress- 
ing case of “cage paralysis,’ extending over a period of one year. 
Only at the late stage of the disease were emaciation and atrophy 
of hind limbs marked features. 
POST-MORTEM SUMMARY. 
Body.—Shows marked atrophy; curvature of spine. Heart.— 
Diastole, normal. Lungs—Pigmented ; otherwise normal. Liver. 
—Congested. Kidneys.—Congested. Spleen and Lymph Nodes. 
—Congested. Stomach and Intestines—Anaemic.  Genito- 
Urinary Tract—Negative. Osseous System—All bones show 
general softening. Thorax laterally compressed. Ribs almost en- 
